Procyanidin B1

Procyanidin B1

CAT N°: 22411
Price:

From €88.00 €74.80

Procyanidin B1 is a polyphenol flavonoid existing as a dimer of (+)-catechin (Item No. 70940) and (?)-epicatechin (Item No. 11807). It inhibits hepatitis C virus RNA replication (EC50 = 72 µM), while (+)-catechin and (?)-epicatechin do not, up to concentrations of 200 µM.{34659} Procyanidin B1 (10 µg/ml) prevents phosphorylation of ERK1/2 and the production of reactive oxygen species (ROS) in THP-1 cells.{34660} It decreases TNF-?, phosphorylated p38 MAPK, and NF-?B levels following LPS administration.{34661}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • (2R,2’R,3R,3’S,4R)-2,2′-bis(3,4-dihydroxyphenyl)-3,3′,4,4′-tetrahydro-[4,8′-bi-2H-1-benzopyran]-3,3′,5,5′,7,7′-hexol
  • Correlated keywords
    • 75923-51-2 hepC hep extracellular?signal?regulated kinase ROS TNFa tumor necrosis factor mitogen?activated protein nuclear kappa-light-chain-enhancer activated B cells TLR4 TLR-4 NFkb
  • Product Overview:
    Procyanidin B1 is a polyphenol flavonoid existing as a dimer of (+)-catechin (Item No. 70940) and (?)-epicatechin (Item No. 11807). It inhibits hepatitis C virus RNA replication (EC50 = 72 µM), while (+)-catechin and (?)-epicatechin do not, up to concentrations of 200 µM.{34659} Procyanidin B1 (10 µg/ml) prevents phosphorylation of ERK1/2 and the production of reactive oxygen species (ROS) in THP-1 cells.{34660} It decreases TNF-?, phosphorylated p38 MAPK, and NF-?B levels following LPS administration.{34661}

We also advise you

Any project? Any challenge? We are in!
Contact us

Headquarters:
Parc d’activités du Pas du Lac
10 bis avenue Ampère

78180 Montigny le Bretonneux
France

Call us
Information
My account
Follow us

Copyright © 2024 BERTIN BIOREAGENT. All rights reserved | Terms & conditions

Secure payment
Subscribe to our newsletter