RGFP109

RGFP109

CAT N°: 21568
Price:

From 92.00 78.20

RGFP109 is a brain-penetrant inhibitor of histone deacetylases (HDACs; IC50s = 60 and 50 nM; Kis = 32 and 5 nM for HDAC1 and HDAC3 in cell-free assays, respectively).{33565} It has been shown to upregulate frataxin mRNA levels in cultured cells obtained from Friedreich’s ataxia patients and in a GAA repeat-based mouse model of Friedreich’s ataxia.{33565}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • N-[6-[(2-aminophenyl)amino]-6-oxohexyl]-4-methyl-benzamide
  • Correlated keywords
    • RGFP-109 HDAC RG2833
  • Product Overview:
    RGFP109 is a brain-penetrant inhibitor of histone deacetylases (HDACs; IC50s = 60 and 50 nM; Kis = 32 and 5 nM for HDAC1 and HDAC3 in cell-free assays, respectively).{33565} It has been shown to upregulate frataxin mRNA levels in cultured cells obtained from Friedreich’s ataxia patients and in a GAA repeat-based mouse model of Friedreich’s ataxia.{33565}

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