BMS 986187

BMS 986187

CAT N°: 21549
Price:

From 48.00 40.80

BMS 986187 is a positive allosteric modulator of ?-opioid receptors.{38565} In the presence of the endogenous ?-opioid receptor agonist leu-enkephalin, BMS 986187 has an average EC50 value of 30 nM for ?-arrestin recruitment, but has little to no activity in the absence of an agonist. It is 100-fold selective for ?- over µ-opioid receptors in the presence of leu-enkephalin and the endogenous µ-opioid receptor agonist endomorphin I, respectively.

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