XL228

XL228

CAT N°: 21506
Price:

From 122.00 103.70

XL228 is a tyrosine kinase inhibitor.{33640,33639} It inhibits the receptor tyrosine kinases insulin-like growth factor 1 receptor (IGF-1R) and FGFR2 (IC50s = 1.6 and 50s = 5, 3.1, 2, and 6.1 nM, respectively). XL228 inhibits proliferation of chronic myelogenous leukemia (CML) and acute lymphoblastic leukemia (ALL) cell lines (IC50s = <100 nM).{60320}

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