AN2728

AN2728

CAT N°: 21455
Price:

From 92.00 78.20

AN2728 is a boron-based, topical anti-inflammatory agent that inhibits phosphodiesterase 4 (PDE4; IC50 = 0.11 µM).{33611} It is less potent against PDE1A, PDE3A, and PDE7A (IC50s = 6.12, 6.41, and 0.73 µM, respectively).{33611} AN2728 suppresses the release of the proinflammatory cytokines TNF-?, IL-2, INF-?, IL-5, and IL-10 with IC50 values of 0.50, 0.59, 0.72, 2.25, and 2.58 µM, respectively.{33611}

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