N6022

N6022

CAT N°: 21269
Price:

45.00 38.25

N6022 is a tight-binding, specific, and fully reversible inhibitor of S-nitrosoglutathione reductase (GSNOR; IC50 = 8 nM; Ki = 2.5 nM).{33360} It is reported to bind in the GSNO substrate binding pocket like a competitive inhibitor, although in kinetic assays it behaves with a mixed uncompetitive mode of inhibition toward the GSNO substrate and a mixed competitive mode of inhibition toward the formaldehyde adduct, S-hydroxymethylglutathione.{33360}

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