Sisomicin

Sisomicin

CAT N°: 21046
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48.00 40.80

Sisomicin is a broad-spectrum aminoglycoside antibiotic originally isolated from M. inyoensis.{42272} It is active against Gram-positive and Gram-negative bacteria including B. subtilis, S. aureus, E. coli, and P. aeruginosa among others (MICs = 0.01-0.75 µg/ml) but is less active against P. multocida and V. coli (MICs = 7.5 and 2.4 µg/ml, respectively). Sisomicin is protective against Gram-positive and Gram-negative bacterial infections in mice with 50% protective dose (PD50s) values ranging from 0.5 to 6 mg/kg.

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