(S)-(+)-Clopi<wbr/>dogrel (sulfate)

(S)-(+)-Clopidogrel (sulfate)

CAT N°: 21002
Price:

From 48.00 40.80

(S)-(+)-Clopidogrel is the functional enantiomer of clopidogrel (Item No. 13657) and a prodrug whose thiol metabolite antagonizes purine binding to the platelet purinergic receptor P2Y12 (Ki = 316 nM in human platelets).{19256} It is metabolized by the cytochrome P450 (CYP) isoform CYP2C19 in rat liver and inhibits ADP-induced platelet aggregation ex vivo.{19259} Formulations containing (S)-(+)-clopidogrel have been used in combination with aspirin to prevent vascular ischemic events in patients with acute coronary syndromes.

We also advise you