Somato<wbr/>statin-14 (human, mouse, rat, porcine, bovine, ovine) (acetate)

Somatostatin-14 (human, mouse, rat, porcine, bovine, ovine) (acetate)

CAT N°: 20809
Price:

From 109.00 92.65

Somatostatin-14 is a natural cyclic peptide hormone derived from the preprohormone, somatostatin.{33263} It is a somatostatin (SST) receptor agonist that binds to SST1, SST2, SST3, SST4, and SST5 (IC50s = 0.22, 0.10, 0.28, 1.23, and 0.30 nM, respectively, in CCL39 cells expressing human recombinant receptors).{42022} It inhibits cAMP accumulation induced by forskolin (Item No. 11018) in CCL39 cells expressing human recombinant SST1, SST2, SST3, SST4, and SST5 (EC50s = 6.16, 4.37, 17.38, 2.95, and 4.67 nM, respectively).{42023} Somatostatin-14 inhibits the release of growth hormone, prolactin, thyrotropin, glucagon, and insulin, as well as other signaling molecules.{33263,5903,12953}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • somatostatin, monoacetate
  • Correlated keywords
    • 52500-64-8 53126-12-8 56451-83-3 38916-34-6 GH-RIF GHRIF SS-14 SS14 cyclic peptide preprohormone prolactin thyrotropin glucagon insulin AGCKNFFWKTFTSC GHIH SRIF
  • Product Overview:
    Somatostatin-14 is a natural cyclic peptide hormone derived from the preprohormone, somatostatin.{33263} It is a somatostatin (SST) receptor agonist that binds to SST1, SST2, SST3, SST4, and SST5 (IC50s = 0.22, 0.10, 0.28, 1.23, and 0.30 nM, respectively, in CCL39 cells expressing human recombinant receptors).{42022} It inhibits cAMP accumulation induced by forskolin (Item No. 11018) in CCL39 cells expressing human recombinant SST1, SST2, SST3, SST4, and SST5 (EC50s = 6.16, 4.37, 17.38, 2.95, and 4.67 nM, respectively).{42023} Somatostatin-14 inhibits the release of growth hormone, prolactin, thyrotropin, glucagon, and insulin, as well as other signaling molecules.{33263,5903,12953}

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