Histone H2A (Xenopus, recombinant)
Histone H2A (Xenopus, recombinant)
Histone H2A is a core histone that forms a dimer with histone H2B.{46631} Two histone H2A/H2B dimers form an octameric...
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€85.00 €72.25
€85.00 €72.25
Marinobufagenin (MBG) is a bufadienolide steroid first isolated from toads of genus Bufo. It can also be excreted by mammalian cells, particularly kidney cells from hypertensive animals.{32977} MBG inhibits the ouabain-resistant ?1 Na+/K+ ATPase subunit (IC50 = 78 nM), impairing a major sodium pump of the kidneys, resulting in natriuresis and arterial hypertension.{32977,32979} Serum and urine levels of MBG are also elevated after cardiac infarction, and a reduced form of MBG, marinobufotoxin, occurs in the plasma of patients with terminal renal failure.{32978,32979} Through its effects on the ?1 Na+/K+ ATPase subunit, MBG has profound immediate and prolonged effects on kidney, heart, and vascular functions.{32979}
Territorial Availability: Available through Bertin Technologies only in France
| Size | 1 mg, 5 mg, 500 µg |
|---|---|
| Shipping | dry ice |
| CAS number | 470-42-8 |
| Molecular formula | C24H32O5 |
| Smiles | O[C@H]1CC[C@@]2(C)[C@@](CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@]3(O5)[C@H]5C[C@@H]4C6=COC(C=C6)=O)(O)C1 |
| Molecular weight | 400,5 |
| Custom code | 2932.99 |
| Formulation | A crystalline solid |
| Purity | ≥98% |
| UNSPSC code | 12352100 |
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Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.
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