Pyrogallol

Pyrogallol

CAT N°: 20347
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Pyrogallol is a natural oxidant that can generate superoxide (O2-) in alkaline solutions through autoxidation to a semiquinone radical.{32348} Importantly, the semiquinone radical can react with O2- in an acidic environment to produce a quinone and H2O2.{32348} Pyrogallol autoxidation is used in superoxide dismutase activity assays.{32348} It can also be used in assays to assess antioxidant capacity.{32347,25176} Pyrogallol is used in some biological systems as an O2- scavenger.{32352} In other biological systems, it is used as an O2- generator.{32351,10231} Pyrogallol effectively scavenges DPPH radical (Item No. 14805) and ABTS+ in vitro.{32349} Pyrogallol is a product of tannin degradation to gallic acid (Item No. 11846) by ruminant microbes and has hepatotoxic and nephrotoxic effects in vivo.{32350}

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