Muri<wbr/>deoxycholic Acid

Murideoxycholic Acid

CAT N°: 20290
Price:

From 140.00 119.00

Murideoxycholic acid (MDCA) is a secondary bile acid produced from ?-muricholic acid (Item No. 20291) and ?-muricholic acid (Item No. 20287).{45190} It is also a metabolite of lithocholic acid (Item No. 20253) in liver S9 fractions from humans and other species.{46202} MDCA prevents gallstone formation in hamsters fed a lithogenic diet but does not resolve gallstones in prairie dogs fed a high cholesterol diet.{37053,37054} Gallstones formed during MDCA administration after a high cholesterol diet are comprised of an insoluble calcium salt of murideoxycholyl taurine.{37054} In humans, MDCA is rapidly absorbed and is metabolized as an endogenous bile acid with a half-life of approximately 3.5 days.{37055}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 5?-3?,6?-dihydroxy-cholan-24-oic acid
  • Correlated keywords
    • 6?-hydroxylithocholic dihydroxycholanoic NSC18166 CDCA a-MCA g-MCA aMCA gMCA
  • Product Overview:
    Murideoxycholic acid (MDCA) is a secondary bile acid produced from ?-muricholic acid (Item No. 20291) and ?-muricholic acid (Item No. 20287).{45190} It is also a metabolite of lithocholic acid (Item No. 20253) in liver S9 fractions from humans and other species.{46202} MDCA prevents gallstone formation in hamsters fed a lithogenic diet but does not resolve gallstones in prairie dogs fed a high cholesterol diet.{37053,37054} Gallstones formed during MDCA administration after a high cholesterol diet are comprised of an insoluble calcium salt of murideoxycholyl taurine.{37054} In humans, MDCA is rapidly absorbed and is metabolized as an endogenous bile acid with a half-life of approximately 3.5 days.{37055}

We also advise you