24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol is an oxysterol and the most abundant oxysterol in mouse ventral midbrain.{43943} It activates liver X receptors (LXRs)...
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€579.00 €492.15
Ubiquitously transcribed tetratricopeptide repeat X (UTX) gene codes for the widely-expressed UTX protein. The UTX gene is localized on the X chromosome and is a homolog of the ubiquitously transcribed mouse Y chromosome (UTY) gene. UTX gene expression has been shown to evade X-chromosome inactivation.{19495} The JmjC-containing UTX protein is a member of the hydroxylase family of enzymes, which are ?-ketoglutarate-dependent Fe (II) oxygenases.{19494} UTX plays a crucial role in epigenetic regulation of gene expression by catalyzing the demethylation of tri-methylated lysine 27 on histone H3.{19496} UTX works in opposition to the polycomb repressive complex 2 (PRC2) group protein EZH2, playing a role in cancers with abberant H3K27 methylation.
Territorial Availability: Available through Bertin Technologies only in France
| Size | 25 µg |
|---|---|
| Shipping | dry ice |
| Molecular weight | 0 |
| Purity | ≥55% estimated by SDS-PAGE |
| Custom code | 3504.00 |
| UNSPSC code | 12352204 |
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24(S),25-epoxy Cholesterol is an oxysterol and the most abundant oxysterol in mouse ventral midbrain.{43943} It activates liver X receptors (LXRs)...
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