CCT007093

CCT007093

CAT N°: 19992
Price:

From 48.00 40.80

CCT007093 is an inhibitor of protein phosphatase 1D (PPM1D, also known as PP2C? and WIP1; IC50 = 8.4 µM), which is encoded by a putative oncogene that is amplified in multiple cancer types.{32263} It does not inhibit PPM1A. CCT007093 selectively inhibits the growth of cancer cells that overexpress PPM1D, including MCF-7, KPL-1, and MCF-3B cells, as well as certain ovarian clear cell carcinoma cells.{32263,32264} CCT007093 has been used to elucidate the mechanism by which PPM1D drives growth in medulloblastoma cells.{32262}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 2E,5E-bis(2-thienylmethylene)-cyclopentanone
  • Correlated keywords
    • CCT-007093 PPM1D PPM-1D protein phosphatase 1D PP2C? PP2Cd PP-2C? PP-2-C? PP-2Cd PP-2-Cd WIP1 WIP-1 oncogene MCF7 KPL1 MCF3B
  • Product Overview:
    CCT007093 is an inhibitor of protein phosphatase 1D (PPM1D, also known as PP2C? and WIP1; IC50 = 8.4 µM), which is encoded by a putative oncogene that is amplified in multiple cancer types.{32263} It does not inhibit PPM1A. CCT007093 selectively inhibits the growth of cancer cells that overexpress PPM1D, including MCF-7, KPL-1, and MCF-3B cells, as well as certain ovarian clear cell carcinoma cells.{32263,32264} CCT007093 has been used to elucidate the mechanism by which PPM1D drives growth in medulloblastoma cells.{32262}

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