Harziano<wbr/>pyridone

Harzianopyridone

CAT N°: 19620
Price:

From 92.00 78.20

Harzianopyridone is an atpenin-like inhibitor of mammalian and nematode mitochondrial complex II (succinate:ubiquinone oxidoreductase; SQR) with IC50 values of 0.017, 0.2, and 2 ?M for bovine, rat, and nematode complex II, respectively.{21748} It also inhibits nematode quinol-fumarate reductase (QFR; IC50 = 0.36 ?M). Harzianopyridone is selective for complex II over complexes I and III in rats and cattle and complex I in nematodes (IC50s >100 ?M). It has antibacterial and antifungal activity (EC50s = 35.9, 42.2, 60.4, and 50.2 ?g/ml against R. solani, S. rolfsii, M. phaseolina, and F. oxysporum, respectively).{41147,41146}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 4-hydroxy-5,6-dimethoxy-3-[(2S,4E)-2-methyl-1-oxo-4-hexen-1-yl]-2(1H)-pyridinone
  • Correlated keywords
    • 126637-69-2 127770-22-3 Rhizoctonia Sclerotium Macrophomina Fusarium
  • Product Overview:
    Harzianopyridone is an atpenin-like inhibitor of mammalian and nematode mitochondrial complex II (succinate:ubiquinone oxidoreductase; SQR) with IC50 values of 0.017, 0.2, and 2 ?M for bovine, rat, and nematode complex II, respectively.{21748} It also inhibits nematode quinol-fumarate reductase (QFR; IC50 = 0.36 ?M). Harzianopyridone is selective for complex II over complexes I and III in rats and cattle and complex I in nematodes (IC50s >100 ?M). It has antibacterial and antifungal activity (EC50s = 35.9, 42.2, 60.4, and 50.2 ?g/ml against R. solani, S. rolfsii, M. phaseolina, and F. oxysporum, respectively).{41147,41146}

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