Podophyllo<wbr/>toxin

Podophyllotoxin

CAT N°: 19575
Price:

48.00 40.80

Podophyllotoxin is a lignan that has been found in Podophyllum and has diverse biological activities.{59991,59992,59993,59994,59995} It inhibits polymerization of isolated chicken brain tubulin (IC50 = 0.6 µM) and induces mitotic arrest at the G2/M phase in CCRF CEM lymphoblastic leukemia cells when used at concentrations ranging from 0.01 to 5 µg/ml.{59992,59993} Podophyllotoxin (5 µM) is protective against herpes simplex virus 1 (HSV-1) infection in Vero cells.{59994} It inhibits the proliferation of several diffuse large B cell lymphoma (DLBCL) cell lines (IC50s = 0.0098-0.017 µM).{59995} Podophyllotoxin is a starting material in the semisynthesis of the anticancer compounds etoposide (Item No. 12092) and teniposide (Item No. 14425).{31220} Formulations containing podophyllotoxin have been used in the treatment of external genital warts.

We also advise you

TAF 10 Peptide

TAF 10 Peptide

TAF10 is one of many protein factors or coactivators associated with RNA polymerase II activity.{16903} One vial of this peptide...

€191.00
View