CWHM12

CWHM12

CAT N°: 19480
Price:

From 55.00 46.75

CWHM12 is an analog of RGD peptide (Item No. 14501), a tripeptide that inhibits integrin-ligand interactions in studies related to cell adhesion, migration, growth, and differentiation.{5588} CWHM12 selectively inhibits ?v integrins (IC50s = 1.8, 0.8, 61, 1.5, and 0.2 nM for ?v?1, ?v?3, ?v?5, ?v?6, and ?v?8, respectively) over ?IIb?3, ?2?1, and ?10?1.{33437} CWHM 12 attenuates liver, lung, and pancreatic fibrosis in mice treated with CCl4 or cerulein.{33437,33439}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • (3S)-N-[3-hydroxy-5-[(1,4,5,6-tetrahydro-5-hydroxy-2-pyrimidinyl)amino]benzoyl]glycyl-3-[3-bromo-5-(1,1-dimethylethyl)phenyl]-?-alanine
  • Correlated keywords
    • CWHM-12 ?v integrins RGD tri-peptide ligand ?v?1 ?v?3 ?v?5 ?v?6 ?v?8 av?1 av?3 av?5 av?6 av?8 ?vb1 ?vb3 ?vb5 ?vb6 avb8 avb3 avb5 avb6 avb8
  • Product Overview:
    CWHM12 is an analog of RGD peptide (Item No. 14501), a tripeptide that inhibits integrin-ligand interactions in studies related to cell adhesion, migration, growth, and differentiation.{5588} CWHM12 selectively inhibits ?v integrins (IC50s = 1.8, 0.8, 61, 1.5, and 0.2 nM for ?v?1, ?v?3, ?v?5, ?v?6, and ?v?8, respectively) over ?IIb?3, ?2?1, and ?10?1.{33437} CWHM 12 attenuates liver, lung, and pancreatic fibrosis in mice treated with CCl4 or cerulein.{33437,33439}

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