Ambroxol (hydro<wbr/>chloride)

Ambroxol (hydrochloride)

CAT N°: 19377
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From 55.00 46.75

Ambroxol is an expectorant and active metabolite of bromhexine.{60276} It decreases short-circuit currents in electrically stimulated isolated canine tracheal epithelial cells when applied submucosally (IC50 = 60 nM).{36407} Ambroxol (100 µM) decreases IL-13-induced production of mucin 5AC (MUC5AC) in primary human airway epithelial cells and inhibits IL-13-induced decreases in the mucociliary transport rate of endogenous particles in the same cells.{33409} Ambroxol increases phenol red secretion, a marker of expectorant activity, in mice when administered at doses of 30, 60, or 120 mg/kg.{60277} Formulations containing ambroxol have been used in the treatment of acute or chronic respiratory conditions.

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