20-HEPE

20-HEPE

CAT N°: 19322
Price:

440.00 374.00

20-HEPE is a metabolite of eicosapentaenoic acid (EPA; Item Nos. 90110 | 21908 | 90110.1) that is formed via ?-oxidation of EPA by cytochrome P450 (CYP) ?-oxidases, including human CYP4F3B.{37628} It activates peroxisome proliferator-activated receptor ? (PPAR?) in COS-7 cells expressing a luciferase reporter when used at a concentration of 10 ?M. 20-HEPE also activates murine transient receptor potential vanilloid receptor 1 (mTRPV1) in vitro but lacks antinociceptive activity in rats.{37629}

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