DG-172 (hydro<wbr>chloride)

DG-172 (hydrochloride)

CAT N°: 19128
Price:

43.00 36.55

DG-172 is an orally available inverse agonist of PPAR?/? (IC50 = 27 nM), down-regulating transcription of ANGPTL4 in mouse myoblasts (IC50 = 9.5 nM).{31239} It alters the differentiation of bone marrow cells, augmenting GM-CSF-induced development into subsets of mature and immature dendritic cells.{31238} Inverse agonists of PPAR?/?, including DG-172, inhibit cancer cell invasion through suppression of ANGPTL4 expression.{31237}

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