CD1530

CD1530

CAT N°: 19062
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From 57.00 48.45

CD1530 is a selective retinoic acid receptor (RAR?) agonist (Kds = 150, 1,500, and 2,750 nM for RAR?, RAR?, and RAR? receptors, respectively).{24736} It demonstrates transcriptional activity at RAR? with an AC50 value of 1.8 nM.{24736} It has been used in combination with bexarotene (Item No. 11571), a retinoid X receptor agonist, to inhibit oral carcinogenesis induced by the carcinogen 4-nitroquinoline 1-oxide in a mouse model of human oral-cavity and esophageal squamous-cell carcinoma.{31184}

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