Temocapril (hydro<wbr>chloride)

Temocapril (hydrochloride)

CAT N°: 18241
Price:

48.00 40.80

Temocapril is a prodrug form of the angiotensin-converting enzyme (ACE) inhibitor temocaprilat (Item No. 22169).{49120} Temocapril is converted to temocaprilat by carboxylesterase 1 (CES1).{26464} It prevents impairment of acetylcholine-induced relaxation in aortic rings isolated from diabetic rats in a model of streptozotocin-induced diabetes.{57887} Temocapril (0.1, 0.3, and 1 mg/kg) inhibits the angiotensin I-induced pressor response in normotensive rats.{49120} It prevents coronary vascular remodeling induced by L-NAME (Item No. 80210) in rats when administered at 0.1 mg/ml in the drinking water.{57888} Temocapril (1 mg/kg) reduces plasma glucose levels in a KKAy mouse model of type 2 diabetes.{57889}

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