Estetrol (hydrate)

Estetrol (hydrate)

CAT N°: 18232
Price:

From 66.00 56.10

Estetrol is an estrogen steroid hormone exclusively produced by fetal liver from estradiol (Item No. 10006315) and estriol (Item No. 10006484) during pregnancy. It binds to estrogen receptors (ERs) with 4-fold higher affinity for ER? over ER? and exhibits estrogenic effects in most tissues expressing ERs (bone, brain, vagina, and endometrium).{29396,29397} In breast tumors, however, estetrol acts as an estrogen antagonist in the presence of estradiol, preventing tumor growth.{29396,29397}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • estra-1,3,5(10)-triene-3,15?,16?,17?-tetrol, hydrate
  • Correlated keywords
    • 30653-26-0 steroid estrogen fetal ER? hormone breast cancer endocrinology pregnancy ER-? ER-a ERa natural hydroxy-estriol 15a-hydroxyestriol 15183-37-6 2055649-81-3
  • Product Overview:
    Estetrol is an estrogen steroid hormone exclusively produced by fetal liver from estradiol (Item No. 10006315) and estriol (Item No. 10006484) during pregnancy. It binds to estrogen receptors (ERs) with 4-fold higher affinity for ER? over ER? and exhibits estrogenic effects in most tissues expressing ERs (bone, brain, vagina, and endometrium).{29396,29397} In breast tumors, however, estetrol acts as an estrogen antagonist in the presence of estradiol, preventing tumor growth.{29396,29397}

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