Fexofenadine (hydro<wbr>chloride)

Fexofenadine (hydrochloride)

CAT N°: 18191
Price:

From 66.00 56.10

Fexofenadine is a histamine H1 receptor antagonist (Ki = 10 nM).{27483} It reverses contraction of isolated rat tracheal strips induced by acetyl-?-methylcholine (Item No. 23092).{36897} Fexofenadine inhibits expression of IL-8 in TNF-?-stimulated HCT116 and COLO 205 cells.{36898} Oral administration of fexofenadine (2 and 10 mg/kg) reduces severity of colitis and phospho-I?B kinase activation in a mouse model of colitis induced by dextran sulfate sodium (DSS; Item No. 23250).

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 4-[1-hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]-?,?-dimethyl-benzeneacetic acid, monohydrochloride
  • Correlated keywords
    • 83799-24-0 138452-21-8 allegra biochemical allergy asthma receptor antagonist antihistamine anti-histamine anti-inflammatory antiinflammatory histamine H1 alernex fastofen feksine fexadyne fexodine fexofen fexofenadine MDL16455A rapido telfast BD vivafeks non-sedating nonsedating selective fexo
  • Product Overview:
    Fexofenadine is a histamine H1 receptor antagonist (Ki = 10 nM).{27483} It reverses contraction of isolated rat tracheal strips induced by acetyl-?-methylcholine (Item No. 23092).{36897} Fexofenadine inhibits expression of IL-8 in TNF-?-stimulated HCT116 and COLO 205 cells.{36898} Oral administration of fexofenadine (2 and 10 mg/kg) reduces severity of colitis and phospho-I?B kinase activation in a mouse model of colitis induced by dextran sulfate sodium (DSS; Item No. 23250).

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