NVP-TAE226

NVP-TAE226

CAT N°: 17685
Price:

From 66.00 56.10

NVP-TAE226 is an inhibitor of focal adhesion kinase (FAK; IC50 = 5.5 nM) and the related proline-rich tyrosine kinase 2-? (PYK2?; IC50 = 5 nM).{32642} It can also inhibit the insulin-like growth factor 1 receptor (IC50 = 0.16 µM) as well as the activity of its downstream target genes such as MAPK and Akt.{32642} NVP-TAE226 has been shown to inhibit glioma and ovarian tumor growth in in vivo tumor models.{15631}

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