O-Phospho-D-Serine

O-Phospho-D-Serine

CAT N°: 17602
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From 180.00 153.00

O-Phospho-D-serine is a phosphorylated form of D-serine, a natural amino acid made from L-serine by serine racemase in the mammalian central nervous system.{28640} It can be dephosphorylated by phosphoserine phosphatase, like its isomer O-phospho-L-serine (L-SOP; Item No. 16151).{28638} Unlike L-SOP, O-phospho-D-serine is a weak agonist of the metabotropic glutamate receptor mGluR4 (IC50 = 1,260 µM vs. 4 µM for L-SOP) and poorly blocks phosphatidylserine receptor-mediated phagocytosis.{28639,28637}

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