Ifosfamide

Ifosfamide

CAT N°: 17562
Price:

From 48.00 40.80

Ifosfamide is a nitrogen mustard alkylating agent used as a chemotherapeutic agent against advanced transitional cell carcinoma.{21579} It is a structural derivative of cyclophosphamide (Item No. 13849) that was developed for improved solubility and antitumor activity. Like cyclophosphamide, ifosfamide serves as a prodrug that is either metabolized to its active DNA alkylating form, isophosphoramide mustard, or catabolized through a dechloroethylation pathway to the neurotoxic and nephrotoxic chloroacetaldehyde.{28725}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • N,3-bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide
  • Correlated keywords
    • 36341-88-5 84711-20-6 66849-34-1 66849-33-0 nitrogen mustard alkylating agent DNA crosslinking chemotherapy isophosphoramide cancer biochemical NSC109724 ifex holoxan 1000 asta Z 4942 Z4942 mitoxana
  • Product Overview:
    Ifosfamide is a nitrogen mustard alkylating agent used as a chemotherapeutic agent against advanced transitional cell carcinoma.{21579} It is a structural derivative of cyclophosphamide (Item No. 13849) that was developed for improved solubility and antitumor activity. Like cyclophosphamide, ifosfamide serves as a prodrug that is either metabolized to its active DNA alkylating form, isophosphoramide mustard, or catabolized through a dechloroethylation pathway to the neurotoxic and nephrotoxic chloroacetaldehyde.{28725}

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