DMPQ (hydro<wbr>chloride)

DMPQ (hydrochloride)

CAT N°: 17551
Price:

From 48.00 40.80

DMPQ is a potent inhibitor of human platelet-derived growth factor receptor ? (PDGFR?, IC50 = 80 nM).{28580} It displays greater than 100-fold selectivity for PDGFR? over other tyrosine and serine/threonine kinases.{28580} DMPQ effectively blocks the PDGF-mediated increase in the protein, Survival Motor Neuron, in fibroblasts from patients with spinal muscular atrophy.{22494}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 5,7-dimethoxy-3-(4-pyridinyl)-quinoline, dihydrochloride
  • Correlated keywords
    • 137206-97-4 biochemical inhibitor kinase protein neuroscience biochemistry signal transduction inhibit HCl PDGFR? PDGFR-? platelet-derived growth factor receptor dihydrochloride potent
  • Product Overview:
    DMPQ is a potent inhibitor of human platelet-derived growth factor receptor ? (PDGFR?, IC50 = 80 nM).{28580} It displays greater than 100-fold selectivity for PDGFR? over other tyrosine and serine/threonine kinases.{28580} DMPQ effectively blocks the PDGF-mediated increase in the protein, Survival Motor Neuron, in fibroblasts from patients with spinal muscular atrophy.{22494}

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