Virginiamycin S1

Virginiamycin S1

CAT N°: 17455
Price:

524.00 445.40

Virginiamycin S1 is a macrolide antibiotic that is a component of the virginiamycin complex (Item No. 14503), which also contains virginiamycin M1 (Item No. 9002172).{39373} It is a member of the streptogramin B group of antibiotics, which bind the 50S ribosomal subunit at the peptidyl transferase center to inhibit initiation and translocation.{27765} They show good bactericidal activity against methicillin-resistant S. aureus (MRSA), although resistance in MRSA is conferred by the cfr gene.{27765,28231} Virginiamycin S1 acts synergistically with virginiamycin M1 to irreversibly inhibit protein synthesis in bacteria.{23008}

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