Amoxapine

Amoxapine

CAT N°: 17347
Price:

48.00 40.80

Amoxapine is a tetracyclic antidepressant with a wide range of pharmacological effects. It inhibits norepinephrine and serotonin reuptake, binding the respective transporters with Kd values of 16 and 58 nM.{22877} It has also been shown to act as either an antagonist or inverse agonist at serotonin 5-HT2A, 2B, 2C, 3, 6, 7 (Kis = 1 and 2 nM for 5-HT2A and 5-HT2C, respectively), dopamine D2, 3, 4 (Kd = 160 nM for D2), ?1-adrenergic (Kd = 50 nM), and histamine H1 (Kd = 25 nM) receptors.{25805,25914}

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