24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol is an oxysterol and the most abundant oxysterol in mouse ventral midbrain.{43943} It activates liver X receptors (LXRs)...
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From €116.00 €98.60
Ibuprofen is a non-steroidal anti-inflammatory drug with diverse biochemical actions, most notably inhibiting COX-1 and COX-2 (IC50s = 2.6 and 1.53 µM, respectively).{1286} It is commonly synthesized as a racemic mixture of (S) and (R) isomers (Item No. item 70280). (R)-Ibuprofen is an enantiomer that is generally not considered a COX inhibitor and is instead thought to be involved in pathways of lipid metabolism as it is incorporated into triglycerides along with fatty acids.{27416} The (R) enantiomer can, however, inhibit NF-?B activation (IC50 = 121.8 µM) in response to T-cell stimulation as well as block superoxide formation, ?-glucuronidase release, and LTB4 generation by stimulated neutrophils (IC50 values range from 40-100 µM).{6935,27418} 50-60% of (R)-ibuprofen is inverted to (S)-ibuprofen (Item No. 16793) in humans after oral administration.{27416,27417,10032}
Territorial Availability: Available through Bertin Technologies only in France
| Size | 100 mg, 250 mg, 500 mg |
|---|---|
| Shipping | dry ice |
| CAS number | 51146-57-7 |
| Molecular formula | C13H18O2 |
| Smiles | OC([C@H](C)C1=CC=C(CC(C)C)C=C1)=O |
| Molecular weight | 206,3 |
| Custom code | 2916.39 |
| Formulation | A crystalline solid |
| Purity | ≥98% |
| UNSPSC code | 12352100 |
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