U-<wbr/>46619

U-46619

CAT N°: 16450
Price:

From 145.00 123.25

U-46619 is a stable analog of the endoperoxide prostaglandin H2, and a TP receptor agonist.{8322} It exhibits properties similar to thromboxane A2, causing platelet shape change and aggregation, and contraction of vascular smooth muscle.{490,714} Mean EC50 values for shape change in human, rat, and rabbit platelets are 4.8, 6.0, and 7.3 nM respectively, and for aggregation are 82, 145, and 65 nM, respectively.{1168}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 9,11-dideoxy-9?,11?-methanoepoxy-prosta-5Z,13E-dien-1-oic acid
  • Correlated keywords
    • endoperoxides PGH2 thromboxanes vasoconstriction analogs TP receptors agonists U46619 atherosclerosis u46619
  • Product Overview:
    U-46619 is a stable analog of the endoperoxide prostaglandin H2, and a TP receptor agonist.{8322} It exhibits properties similar to thromboxane A2, causing platelet shape change and aggregation, and contraction of vascular smooth muscle.{490,714} Mean EC50 values for shape change in human, rat, and rabbit platelets are 4.8, 6.0, and 7.3 nM respectively, and for aggregation are 82, 145, and 65 nM, respectively.{1168}

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