RHC-<wbr/>80267

RHC-80267

CAT N°: 16432
Price:

From 66.00 56.10

RHC-80267 is an inhibitor of diacylglycerol lipase (DAGL; IC50 = 4 µM for the canine platelet enzyme).{27089} It also inhibits the serine hydrolases KIAA1363, fatty acid amide hydrolase (FAAH), BAT5, phospholipase A2 (PLA2), hormone-sensitive lipase (HSL), and acetylcholinesterase (AChE) by greater than 60% when used at a concentration of 50 µM.{16688} RHC-80267 (0.1-10 µM) potentiates ACh-induced relaxation of isolated rat mesenteric arteries.{58483}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 1,1’-[O,O’-[1,6-hexanediylbis(iminocarbonyl)]dioxime]
  • Correlated keywords
    • diacylglycerol lipase DAGL inhibitor of diacylglycerol DAG second messenger protein kinase C PKC cell cellular arachidonic acid release phospholipase A2 C PLA2 PLC initiate activation activate enhance acetylcholine-induced AChE-induced smooth muscle relaxation in vitro U 57908 U57908 RHC80267 inhibit
  • Product Overview:
    RHC-80267 is an inhibitor of diacylglycerol lipase (DAGL; IC50 = 4 µM for the canine platelet enzyme).{27089} It also inhibits the serine hydrolases KIAA1363, fatty acid amide hydrolase (FAAH), BAT5, phospholipase A2 (PLA2), hormone-sensitive lipase (HSL), and acetylcholinesterase (AChE) by greater than 60% when used at a concentration of 50 µM.{16688} RHC-80267 (0.1-10 µM) potentiates ACh-induced relaxation of isolated rat mesenteric arteries.{58483}

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