5'-Deoxy-5'-methylthioadenosine

5′-Deoxy-5′-methylthioadenosine

CAT N°: 15593
Price:

From 62.00 52.70

5′-Deoxy-5′-methylthioadenosine (MTA) is an intermediate in the generation of adenine and methionine that is produced by the decarboxylation of S-adenosylmethionine.{25496} This nucleoside is a potent agonist of adenosine receptors (Kis = 0.15, 1.13, 13.9, and 0.68 ?M for A1, A2A, A2B, and A3, respectively).{25499} At higher concentrations, MTA inhibits several enzymes, including protein carboxylmethyltransferase (Ki = 41 ?M), S-adenosylhomocysteine hydrolase, SET methyltransferases, and spermidine and spermine synthases.{25497,25496,16624,25500}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 5′-S-methyl-5′-thio-adenosine
  • Correlated keywords
    • NSC335422
  • Product Overview:
    5′-Deoxy-5′-methylthioadenosine (MTA) is an intermediate in the generation of adenine and methionine that is produced by the decarboxylation of S-adenosylmethionine.{25496} This nucleoside is a potent agonist of adenosine receptors (Kis = 0.15, 1.13, 13.9, and 0.68 ?M for A1, A2A, A2B, and A3, respectively).{25499} At higher concentrations, MTA inhibits several enzymes, including protein carboxylmethyltransferase (Ki = 41 ?M), S-adenosylhomocysteine hydrolase, SET methyltransferases, and spermidine and spermine synthases.{25497,25496,16624,25500}

We also advise you