24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol is an oxysterol and the most abundant oxysterol in mouse ventral midbrain.{43943} It activates liver X receptors (LXRs)...
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Fidaxomycin is a natural macrocyclic antibiotic that inhibits RNA polymerase with selectivity for Gram-positive bacteria over Gram-negative bacteria (IC50s = 0.4 and 6 ?M, respectively).{25092} It has potent antibacterial activity against most Gram-positive bacteria and effectively targets the Gram-positive C. difficile (MIC = 12 ng/ml).{25092} Orally administered fidaxomycin exhibits minimal systemic bioavailability resulting in maximal gastrointestinal tract distribution.{25092} Fidaxomycin is effective in clearing C. difficile infections while sparing Gram-negative bacteria in the gut.{25090,25089}
Territorial Availability: Available through Bertin Technologies only in France
| Size | 10 mg, 100 mg, 50 mg |
|---|---|
| Shipping | dry ice |
| CAS number | 873857-62-6 |
| Molecular formula | C52H74Cl2O18 |
| Smiles | O=C1/C(CO[C@H]2[C@@H](OC)[C@@H](O)[C@H](OC(C3=C(CC)C(Cl)=C(O)C(Cl)=C3O)=O)[C@@H](C)O2)=C/C=C/C[C@H](O)/C(C)=C[C@H](CC)[C@@H](O[C@]4([H])OC(C)(C)C(OC(C(C)C)=O)[C@H](O)[C@@H]4O)/C(C)=CC(C)=C/C[C@]([C@H](O)C)([H])O1, O=C1/C(CO[C@H]2[C@@H](OC)[C@@H](O)[C@H](OC(C3=C(CC)C(Cl)=C(O)C(Cl)=C3O)=O)[C@@H](C)O2)=C/C=C/C[C@H](O)/C(C)=C[C@H](CC)[C@@H](O[C@]4([H])OC(C)(C)C(OC(C(C)C)=O)[C@H](O)[C@@H]4O)/C(C)=CC(C)=C/C[C@]([C@H](O)C)([H])O1, O=C1/C(CO[C@H]2[C@@H](OC)[C@@H](O)[C@H](OC(C3=C(CC)C(Cl)=C(O)C(Cl)=C3O)=O)[C@@H](C)O2)=C/C=C/C[C@H](O)/C(C)=C[C@H](CC)[C@@H](O[C@]4([H])OC(C)(C)C(OC(C(C)C)=O)[C@H](O)[C@@H]4O)/C(C)=CC(C)=C/C[C@]([C@H](O)C)([H])O1 |
| Molecular weight | 1058 |
| Custom code | 2907.29 |
| Formulation | A crystalline solid |
| Purity | ≥95% |
| UNSPSC code | 12352100 |
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24(S),25-epoxy Cholesterol is an oxysterol and the most abundant oxysterol in mouse ventral midbrain.{43943} It activates liver X receptors (LXRs)...
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