Butein

Butein

CAT N°: 15371
Price:

From 48.00 40.80

Butein is a plant polyphenol that is classified as a chalcone, due to the propenone linkage between the phenol groups. Like other polyphenols, butein is a potent antioxidant and affects the numerous pathways modulated by oxidant tone, including inflammation, cancer, and immune response.{25061,25058,25057} It inhibits 5-lipoxygenase, the enoyl-acyl-carrier protein reductase of P. falciparum, angiotensin-converting enzyme, and Src kinase (IC50 or Ki values of 0.01, 2.97, 0.73, and 65 ?M, respectively).{25060,25062,25056,25063} Butein is also a sirtuin activator, increasing trichostatin A (Item No. 89730)-insensitive deacetylase activity.{12143,20124}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • (2E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-2-propen-1-one
  • Correlated keywords
    • natural products oxidative injury injuries antioxidants anti-oxidants anti oxidants inflammation cancers inhibitors inhibits inhibitions histones deacetylases plants polyphenols phenols chalcones potent oxidant tones immune responses 5-lipoxygenase 5-LO 5-LOX P. falciparum angiotensins Src activators activates TSA tetrahydroxy enoyl-acyl-carrier proteins reductases kinases sirtuins activators trichostatins A
  • Product Overview:
    Butein is a plant polyphenol that is classified as a chalcone, due to the propenone linkage between the phenol groups. Like other polyphenols, butein is a potent antioxidant and affects the numerous pathways modulated by oxidant tone, including inflammation, cancer, and immune response.{25061,25058,25057} It inhibits 5-lipoxygenase, the enoyl-acyl-carrier protein reductase of P. falciparum, angiotensin-converting enzyme, and Src kinase (IC50 or Ki values of 0.01, 2.97, 0.73, and 65 ?M, respectively).{25060,25062,25056,25063} Butein is also a sirtuin activator, increasing trichostatin A (Item No. 89730)-insensitive deacetylase activity.{12143,20124}

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