Clotrimazole

Clotrimazole

CAT N°: 15278
Price:

From 48.00 40.80

Clotrimazole is an imidazole antifungal that is active against a wide variety of fungal forms and is effective in many types of fungal infections.{25589,25585,25586,25584} It tightly binds sterol 14-? demethylase isoform B from A. fumigatus (KD = 103 nM) and, like other imidazoles, disturbs the fungal cell membrane.{25587,25584} In mammalian cells, clotrimazole potently inhibits the calcium-dependent potassium channels Kv1.3 and IK-1 (IC50 = 6.0 and 0.07 µM, respectively).{25588}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 1-[(2-chlorophenyl)diphenylmethyl]-1H-imidazole
  • Correlated keywords
    • 117829-?71-?7 inhibitors ions channels blockers infectious diseases imidazole antifungal anti-fungal anti fungal infections inhibits inhibitions pumps blockers sterol 14-?-demethylase 14-a-demethylase 14-alpha-demethylase 14-.alpha.-demethylase isoforms B A. fumigatus aspergillus agisten BAYs 5097 BAY5097 BAY-5097 BAY-B BAYB B canesten canesten canifug clotrimazole desamix F empecid femcare gyne-lotrimin gyne lotrimin 7 seven locasten AF creams solutions Jock-itch jock itch lotions monobaycuten Mycelex G OTC troche mycofug mycosporin NSCs 257473 NSC-257473 NSC257473 pedisafe plimycol rimazole tibatin trimysten veltrim
  • Product Overview:
    Clotrimazole is an imidazole antifungal that is active against a wide variety of fungal forms and is effective in many types of fungal infections.{25589,25585,25586,25584} It tightly binds sterol 14-? demethylase isoform B from A. fumigatus (KD = 103 nM) and, like other imidazoles, disturbs the fungal cell membrane.{25587,25584} In mammalian cells, clotrimazole potently inhibits the calcium-dependent potassium channels Kv1.3 and IK-1 (IC50 = 6.0 and 0.07 µM, respectively).{25588}

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