ML-<wbr/>239

ML-239

CAT N°: 15188
Price:

From 48.00 40.80

ML-239 is an inhibitor of cancer stem cells, displaying greater than 23-fold selective inhibition of a breast cancer stem cell-like cell line (EC50 = 1.18 µM) over an isogenic control cell line (EC50 = 27.6 µM).{24522,24523,24524} It is also toxic to the breast carcinoma cell line MDA-MB-231.{24522} ML-239 alters the expression of genes in the MAPK, NF-?B, and inflammatory cytokine pathways.{24522,24524} It is stable in saline and modestly stable in human plasma.{24523}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 2-(2,4,6-trichlorophenoxy)-acetic acid, (2E)-2-(1H-pyrrol-2-ylmethylene)hydrazide
  • Correlated keywords
    • inhibitors cancers genes regulations stems cells researchs inhibits inhibitions breasts ML239 MLs 239 selective cell-like like lines toxic carcinomas MDA-MB-231 MDAMB231 MDA MB 231 genes saline glutathione humans plasmas CIDs CID-49843203 CID49843203 ML-239 23-fold 23 folds isogenic controls expressions MAPK NF-kB NK-kappaB NF-.kappa.B NFs kB ?B NF-?B kappaB .kappa.B inflammatory cytokines pathways stable CID-49843203 CID49843203 CID 49843203
  • Product Overview:
    ML-239 is an inhibitor of cancer stem cells, displaying greater than 23-fold selective inhibition of a breast cancer stem cell-like cell line (EC50 = 1.18 µM) over an isogenic control cell line (EC50 = 27.6 µM).{24522,24523,24524} It is also toxic to the breast carcinoma cell line MDA-MB-231.{24522} ML-239 alters the expression of genes in the MAPK, NF-?B, and inflammatory cytokine pathways.{24522,24524} It is stable in saline and modestly stable in human plasma.{24523}

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