Sulbactam

Sulbactam

CAT N°: 15024
Price:

From 55.00 46.75

?-Lactams are a large class of antibiotics that includes penicillins, cephalosporins, carbapenems, and monobactams.{25960} Resistance against ?-lactam antibiotics can result from the production of ?-lactamases, which is a common mechanism employed by Gram-negative bacteria.{25960,27765} Sulbactam is a penicillanic acid sulfone that acts as an irreversible inhibitor of ?-lactamases.{27903} It is effective against a wide variety of serine ?-lactamases produced by common Gram-negative and Gram-positive aerobes and anaerobes.{27902,27900,27901} However, it is not effective against metallo-?-lactamases, cephalosporinases, or oxacillinases.{27901}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • (2S,5R)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 4,4-dioxide
  • Correlated keywords
    • biochemical inhibitor antibiotic S,S-dioxide sulfone Betamaze irreversible inhibit ?-lactam ?-lactamase sulfone serine Gram-negative positive aerobe anaerobe
  • Product Overview:
    ?-Lactams are a large class of antibiotics that includes penicillins, cephalosporins, carbapenems, and monobactams.{25960} Resistance against ?-lactam antibiotics can result from the production of ?-lactamases, which is a common mechanism employed by Gram-negative bacteria.{25960,27765} Sulbactam is a penicillanic acid sulfone that acts as an irreversible inhibitor of ?-lactamases.{27903} It is effective against a wide variety of serine ?-lactamases produced by common Gram-negative and Gram-positive aerobes and anaerobes.{27902,27900,27901} However, it is not effective against metallo-?-lactamases, cephalosporinases, or oxacillinases.{27901}

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