Glutathione ethyl ester

Glutathione ethyl ester

CAT N°: 14953
Price:

From 72.00 61.20

Glutathione (GSH) ethyl ester is a cell-permeable derivative of GSH (Item No. 10007461), a nucleophilic co-substrate to glutathione transferases.{25023} It increases mitochondrial GSH levels in C38 and IB3-1 epithelial lung cystic fibrosis cells when used at a concentration of 10 mM.{25025} GSH ethyl ester (10 mM) decreases reactive oxygen species (ROS) levels and TNF-?-induced IL-8 secretion in IB3-1 cells. GSH ethyl increases mitochondrial complex I, also known as NADH dehydrogenase, function and reduces depolarization of the mitochondrial membrane potential in IB3-1 when used at concentrations of 10 mM and 1mM, respectively. It decreases lipid oxidation and ferroptosis in cystine-deficient PANC-1, AsPC-1, BxPC-3, and S2-013 pancreatic cancer cells.{59136} GSH ethyl ester increases the viability of irradiated human lymphoid cells when used at a concentration of 5 mM.{25023}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • L-?-glutamyl-L-cysteinyl-glycine, 3-ethyl ester
  • Correlated keywords
    • 118421-50-4 mono-ethyl cosubstrate C-38 IB31 TNF? IL8 PANC1 AsPC1 BxPC3 S2013
  • Product Overview:
    Glutathione (GSH) ethyl ester is a cell-permeable derivative of GSH (Item No. 10007461), a nucleophilic co-substrate to glutathione transferases.{25023} It increases mitochondrial GSH levels in C38 and IB3-1 epithelial lung cystic fibrosis cells when used at a concentration of 10 mM.{25025} GSH ethyl ester (10 mM) decreases reactive oxygen species (ROS) levels and TNF-?-induced IL-8 secretion in IB3-1 cells. GSH ethyl increases mitochondrial complex I, also known as NADH dehydrogenase, function and reduces depolarization of the mitochondrial membrane potential in IB3-1 when used at concentrations of 10 mM and 1mM, respectively. It decreases lipid oxidation and ferroptosis in cystine-deficient PANC-1, AsPC-1, BxPC-3, and S2-013 pancreatic cancer cells.{59136} GSH ethyl ester increases the viability of irradiated human lymphoid cells when used at a concentration of 5 mM.{25023}

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