Ac-DEVD-<em>p</em>NA

Ac-DEVD-pNA

CAT N°: 14460
Price:

From 48.00 40.80

During apoptosis, activated caspase-3 cleaves several substrates, including poly(ADP-ribose) polymerase, which it specifically targets at the amino sequence DEVD.{22861} Ac-DEVD-pNA is a para-nitro aniline chromophore cleaved by caspases (Km = 18, 11, 32, 180, and 12 µM for caspases-1, -3, -4, -6, and -7, respectively).{7213} It is not cleaved by caspase-2.{7213} Cleavage is monitored colorimetrically at 405 nm.

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