1,5-<wbr/>Isoquinolinediol

1,5-Isoquinolinediol

CAT N°: 14438
Price:

From 58.00 49.30

The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis.{22577} 1,5-Isoquinolinediol is an inhibitor of poly(ADP-ribose) synthetase (PARP1; IC50 = 0.39 ?M).{22573} It has been used to study the role of PARP1 in both DNA repair and oxidant stress-induced cell death.{22579,22576,22574} This compound can be used with cells in culture and in animals.{22576,22575,22578}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 5-hydroxy-1(2H)-isoquinolinone
  • Correlated keywords
    • Inhibitors oxidative injury apoptosis DNA damage inhibits inhibitions injuries poly(ADP-ribose) ADP PARPs PARP1 PARP-1 repari oxidant stress cells death induced 40048-26-8 NSC65585 NSC-65585 NSCs 65585
  • Product Overview:
    The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis.{22577} 1,5-Isoquinolinediol is an inhibitor of poly(ADP-ribose) synthetase (PARP1; IC50 = 0.39 ?M).{22573} It has been used to study the role of PARP1 in both DNA repair and oxidant stress-induced cell death.{22579,22576,22574} This compound can be used with cells in culture and in animals.{22576,22575,22578}

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