Verapamil (hydro<wbr>chloride)

Verapamil (hydrochloride)

CAT N°: 14288
Price:

From 43.00 36.55

Verapamil is the prototypical blocker of L-type calcium channels that produces excitation-contraction uncoupling in cardiac muscle by preventing the slow-inward current of calcium ions.{22485} Verapamil can also block calcium fluxes in vascular smooth muscle. It has both peripheral and coronary vasodilator effects (IC50 = 0.38 ?M in guinea pig aortic strip) and has been used to control hypertension, angina, cardiac arrhythmia, and vascular headaches.{22481,22479,22478} Verapamil has also been used in cell biology as an inhibitor of drug efflux pump proteins such as P-glycoprotein, which are often over-expressed in certain tumor cell lines.{20755}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • ?-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-?-(1-methylethyl)-benzeneacetonitrile, monohydrochloride
  • Correlated keywords
    • 52-53-9 23313-68-0 219944-20-4 Akilen Anpec Apo-Verap Apoacor Arapamyl Azupamil Berkatens Calan-SR Calaptin-240SR 80 Cardiabeltin Cardiagutt Cardibeltin Caveril Civicor Coraver Cordilox-SR Corpamil Covera-HS Dignover Dilacoran-HTA Drosteakard Finoptin Flamon Geangin Hexasoptin Ikacor Ikapress Iproveratril Iso-Card-SR Isoptin-SR Isoptine Isoptino Izoptin Lekoptin LU-20175 LU20175 Manidon Novo-Veramil NSC272366 NSC657799 Quasar Ravamil-SR Securon Univer Vasolan Vasomil Vasopten Veracaps-SR Veracim Veracor Verahexal Veraloc Veramex Veramil Verapin Verapress-240SR Veraptin Verdilac Verelan-SR Verexamil Verogalid-ER Verpal Vetrimil
  • Product Overview:
    Verapamil is the prototypical blocker of L-type calcium channels that produces excitation-contraction uncoupling in cardiac muscle by preventing the slow-inward current of calcium ions.{22485} Verapamil can also block calcium fluxes in vascular smooth muscle. It has both peripheral and coronary vasodilator effects (IC50 = 0.38 ?M in guinea pig aortic strip) and has been used to control hypertension, angina, cardiac arrhythmia, and vascular headaches.{22481,22479,22478} Verapamil has also been used in cell biology as an inhibitor of drug efflux pump proteins such as P-glycoprotein, which are often over-expressed in certain tumor cell lines.{20755}

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