4-Methyl<wbr/>amphetamine (hydro<wbr/>chloride)

4-Methylamphetamine (hydrochloride)

CAT N°: 14215
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4-Methylamphetamine (4-MA) (hydrochloride) (Item No. 14215) is an analytical reference standard categorized as an amphetamine. 4-MA acts on norepinephrine (NE), dopamine (DA), and serotonin (5-HT) transporters to increase extracellular levels of these neurotransmitters. In vitro, the potencies of 4-MA for NE and DA release are similar to those of D-amphetamine with EC50 values of 22.2 and 7.2 nM for NE and 44.1 and 8.0 nM for DA, respectively.{36006} 4-MA is more potent than D-amphetamine at releasing serotonin (EC50s = 53.4 and 1,756 nM, respectively). In rats, 4-MA acts as an agonist at 5-HT1A receptors and induces hypothermia.{36005} It is found as a contaminant in amphetamine, and ingestion has been associated with severe intoxication and fatalities.{36004} This product is intended for research and forensic applications.

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