OAC3

OAC3

CAT N°: 14104
Price:

From 66.00 56.10

Octamer-binding transcription factor 4 (Oct4) is a transcription factor which, with Sox2, Klf4, and c-Myc, is involved in the reprogramming of somatic cells to produce pluripotent stem cells.{22412,22414} OAC3 is an Oct4-activating compound which activates expression through the Oct4 gene promoter.{22003} In cells expressing Oct4 with Sox2, Klf4, and c-Myc, OAC3 (1 ?M) enhances reprogramming efficiency by increasing the rate of production of induced pluripotent stem cells from embryonic fibroblasts.{22003}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 4-fluoro-N-1H-indol-5-yl-benzamide
  • Correlated keywords
    • stems cells research genes regulations Oct-4 Oct4 Octs 4 OAC-3 OACs 3 activating compounds Sox-2 Sox2 Soxs Klf4 Klf-4 Klf 4 c-Myc Myc pluripotent embryonic fibroblasts TFs transcription factors somatic expressions reprogramming differentiations promoters
  • Product Overview:
    Octamer-binding transcription factor 4 (Oct4) is a transcription factor which, with Sox2, Klf4, and c-Myc, is involved in the reprogramming of somatic cells to produce pluripotent stem cells.{22412,22414} OAC3 is an Oct4-activating compound which activates expression through the Oct4 gene promoter.{22003} In cells expressing Oct4 with Sox2, Klf4, and c-Myc, OAC3 (1 ?M) enhances reprogramming efficiency by increasing the rate of production of induced pluripotent stem cells from embryonic fibroblasts.{22003}

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