Acivicin

Acivicin

CAT N°: 14003
Price:

From 75.00 63.75

Acivicin is a glutamine analog that irreversibly inhibits glutamine-dependent amidotransferases involved in nucleotide and amino acid biosynthesis (Kis = 10 and 560 ?M for anthranilate synthase and glutamate synthase, respectively).{21903,21899} It also reversibly inhibits ?-glutamyl transpeptidase.{21902,21901} Acividin has been used to elucidate aspects of glutathione metabolism and has known anti-tumorigenic activity.{21898,21900,21899,21897}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • ?S-amino-3-chloro-4,5S-dihydro-5-isoxazoleacetic acid
  • Correlated keywords
    • AT125 AT-125 NSC163501 NSC-163501 U42126 U-42126 glutamines glutamine-dependent amidotransferases inhibitors nucleotides anthranilate synthases glutamates synthase ?-glutamyl transpeptidase glutathione metabolism anti-tumors anti-cancers analogs inhibits inhibitions amidotransferases biosynthesis anti-tumorigenic antitumorigenics
  • Product Overview:
    Acivicin is a glutamine analog that irreversibly inhibits glutamine-dependent amidotransferases involved in nucleotide and amino acid biosynthesis (Kis = 10 and 560 ?M for anthranilate synthase and glutamate synthase, respectively).{21903,21899} It also reversibly inhibits ?-glutamyl transpeptidase.{21902,21901} Acividin has been used to elucidate aspects of glutathione metabolism and has known anti-tumorigenic activity.{21898,21900,21899,21897}

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