Salidroside

Salidroside

CAT N°: 13628
Price:

From 179.00 152.15

Salidroside is a glycoside that has been found in R. rosea and has diverse biological activities, including antioxidant, anti-apoptotic, neuroprotective, and anti-inflammatory properties.{17556,48899,48900,48901,18152} It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) and ABTS (Item No. 27317) radicals with EC50 values of 81.54 and 30.94 µg/ml, respectively, in cell-free assays.{48899} Salidroside (50 and 100 µM) inhibits apoptosis and production of reactive oxygen species (ROS) induced by amyloid-? (25-35) (A? (23-35)) in SH-SY5Y neuroblastoma cells.{48900} It decreases infarct volume by 17.9% in a rat model of focal cerebral ischemia-reperfusion injury induced by transient middle cerebral artery occlusion (MCAO) when administered at a dose of 12 mg/kg.{48901} Salidroside (20, 50, and 100 mg/kg, p.o.) increases survival and reduces plasma alanine aminotransferase (ALT), aspartate aminotransferase (AST), TNF-?, and malondialdehyde (MDA) levels in a mouse model of liver injury induced by acetaminophen (Item No. 10024).{18152}

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