Bisindolyl<wbr/>maleimide IX (mesylate)

Bisindolylmaleimide IX (mesylate)

CAT N°: 13334
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From 66.00 56.10

Bisindolylmaleimide IX (BIM IX) is a potent, cell-permeable inhibitor of protein kinase C (PKC) isoforms (IC50 = 5, 24, 14, 27, and 24 nM for PKC-?, PKC-?I, PKC-?II, PKC-?, and PKC-?, respectively).{17342} It is a poor inhibitor of protein kinase A (PKA, IC50 = 0.9 ?M) and calcium/calmodulin kinase II (IC50 = 17 ?M). BIM IX also inhibits glycogen synthase kinase 3 (IC50 = 6.8 nM).{17379}

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