IKK-16 (hydro<wbr>chloride)

IKK-16 (hydrochloride)

CAT N°: 13313
Price:

From 140.00 119.00

IKK-16 is a potent inhibitor of I?B kinases (IKKs), displaying IC50 values of 200, 40, and 70 nM for IKK?, IKK?, and IKK complex, respectively, in cell-free assays.{29522} It is effective in cells and in animals and has been used delineate the role of NF-?B signaling in diverse contexts.{29517,29521,29518,29519} IKK-16 has also been reported to inhibit protein kinase D isoforms and the ATP-binding cassette (ABC) transporter ABCB1.{29520,29516}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • [4-[(4-benzo[b]thien-2-yl-2-pyrimidinyl)amino]phenyl][4-(1-pyrrolidinyl)-1-piperidinyl]-methanone, monohydrochloride
  • Correlated keywords
    • 873225-46-8 I?B IKK IKK16 inhibitor IKB
  • Product Overview:
    IKK-16 is a potent inhibitor of I?B kinases (IKKs), displaying IC50 values of 200, 40, and 70 nM for IKK?, IKK?, and IKK complex, respectively, in cell-free assays.{29522} It is effective in cells and in animals and has been used delineate the role of NF-?B signaling in diverse contexts.{29517,29521,29518,29519} IKK-16 has also been reported to inhibit protein kinase D isoforms and the ATP-binding cassette (ABC) transporter ABCB1.{29520,29516}

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