16(R)-<wbr/>Iloprost

16(R)-Iloprost

CAT N°: 13076
Price:

From 226.00 192.10

Iloprost is a second generation structural analog of prostacyclin (PGI2) with about ten-fold greater potency than the first generation stable analogs, typified by carbaprostacyclin.{3347} Iloprost binds with equal affinity to the recombinant human IP and EP1 receptors with a Ki value of 11 nM.{8322} Most preparations of iloprost contain 16(S) and 16(R) stereoisomers. 16(R)-Iloprost inhibits platelet aggregation with an IC50 value of 65 nM.{16394}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 6,9?-methylene-11?,15S-dihydroxy-16R-methyl-prosta-5E,13E-dien-18-yn-1-oic acid
  • Correlated keywords
    • prostacyclin platelet aggregation IP receptors EP vasodilation pulmonary hypertension stereoisomers inhibits inhibitors inhibition iloprosts PGI2
  • Product Overview:
    Iloprost is a second generation structural analog of prostacyclin (PGI2) with about ten-fold greater potency than the first generation stable analogs, typified by carbaprostacyclin.{3347} Iloprost binds with equal affinity to the recombinant human IP and EP1 receptors with a Ki value of 11 nM.{8322} Most preparations of iloprost contain 16(S) and 16(R) stereoisomers. 16(R)-Iloprost inhibits platelet aggregation with an IC50 value of 65 nM.{16394}

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